Dr Mark Wylie


Assistant Lecturer
Department of Aerospace, Mechanical & Electronic Engineering

e: mark.wylie@setu.ie t: 059 9175485

Dr Mark Wylie is a BEng graduate in Mechanical Engineering from Dublin Institute of Technology (DIT, 2008). In 2012, he was awarded his PhD in Biomedical Engineering from DIT for his research in the area of ultrasonic angioplasty, characterising soft tissue ablation using ultrasonically vibrating waveguides. Dr Wylie is also a postgraduate student from the International Space University (ISU, SSP Barcelona 2008) and has been working in the aerospace industry as a Mechanical Space Systems Engineer since 2012, designing and qualifying rugged Data Acquisition (DAq) systems on-board manned and un-manned spacecraft, including the International Space Station (ISS). He is currently a full-time lecturer and researcher with the Aerospace, Mechanical and Electronics Engineering (AME) Department within the School of Engineering at SETU Carlow. He is a member of the SETU Carlow Engineering Centre of Research and Enterprise (engCORE) team.

  • Research Interests
  • Publications
  • Research Supervision

Research Interests

Dr Wylie’s research interests lie in areas relating to Mechanical, Biomedical, Aerospace and Electronic Engineering. Specifically, minimally invasive ultrasonic (US) medical devices, soft tissue perforation and ablation, US acoustic FEA, structural FEA for spacecraft acceleration load cases, isolation of piezoelectric devices on PCBs, vibration isolation for electronic equipment and deployable structures and experimental payloads for sounding rockets.



  • Increased Susceptibility of Arterial Tissue to Wire Perforation with the Application of High Frequency Mechanical Vibrations. Mark P. Wylie, Garrett B. McGuinness and Graham P. Gavin. IEEE Transactions on Biomedical Engineering. Manuscript accepted December 2011. DOI 10.1109/TBME.2012.2184286.
  • Soft Tissue Cutting with Ultrasonic Mechanical Waveguides. Mark. P. Wylie, Garrett McGuinness and Graham. P. Gavin. International Congress on Ultrasonics, Gdansk, Poland, September, 2011. Conference paper.
  • Deployment and Characterisation of a Telescopic Boom for Sounding Rockets. Mark P. Wylie, Paul Duffy. Dinesh Vather, Stephen Curran and John Alan Keegan. 20th ESA Symposium on European Rocket and Balloon Programmes and Related Research (PAC), Hyeres, France, 2011.
  • Perforation of Arterial Tissue using Low Frequency Ultrasound Delivered via NiTi Waveguides. Mark P. Wylie, Garrett McGuinness and Graham Gavin. Bioengineering In Ireland Conference, Galway, Ireland, January, 2011. Conference abstract.
  • A Novel Telescopic Boom Deployment System for Use in Upper Atmosphere Research. Mark P. Wylie, Paul Duffy. Dinesh Vather, Stephen Curran and John Alan Keegan. International Manufacturing Conference, Mayo, Ireland, 2010.
  • A Linear Finite Element Acoustic Fluid-Structure Model of Ultrasonic Angioplasty in vivo. Mark P. Wylie, Garrett McGuinness and Graham Gavin. International Journal of Numerical Methods in Biomedical Engineering. Volume 26, Issue 7, pages 828 – 842, July 2010.
  • Ablation of Chronic Total Occlusions using Kilohertz-Frequency Mechanical Vibrations in Minimally Invasive Angioplasty Procedures. G.B. McGuinness, Mark P. Wylie, G.P. Gavin. Critical Reviews in Biomedical Engineering. Volume 38, Issue 6, pages 511 – 531, July 2010.
  • Ultrasonic Angioplasty: Assessing the Risk of Arterial Perforation. Mark P. Wylie, Garrett McGuinness and Graham Gavin. UK Society for Biomaterials Conference, Belfast, Northern Ireland, July, 2009. Conference paper.
  • Therapeutic Ultrasound Angioplasty: The Risk of Arterial Perforation. An In Vitro Study.  Mark P. Wylie, Garrett McGuinness and Graham Gavin. IEEE Engineering in Medicine Conference, Minneapolis, USA, September, 2009. Conference paper.
  • A Numerical Acoustic Fluid-Structure in Vivo Model of Ultrasonic Angioplasty in a Peripheral Artery. Mark P. Wylie, Garrett McGuinness and Graham Gavin. Conference on Computational & Mathematical Biomedical Engineering, Swansea, UK, June, 2009. Conference paper
  • Numerical Investigation of the Effects of Ultrasonic Angioplasty: Thermal Heating and Acoustic Streaming. Mark P. Wylie, Garrett McGuinness and Graham Gavin. Northern Ireland Biomedical Engineering Society Conference, Belfast, Northern Ireland, March, 2008. Conference abstract.







Current research projects include:
  • Atherosclerotic Tissue Mocks for purpose of Medical Device Development and Device Efficiency/Injury Classification [open call].
  • Soft Tissue Ablation using Ultrasonically Vibrating Wire Waveguide Cutters [open call].
  • Structural Analysis of an Electronics Chassis and PCBs for Launcher Environment [open call].
  • Structural Health Monitoring of Aircraft using Recurrence Quantification Analysis (RQA).